![]() ![]() The two salts of metoprolol have been compared in a haemodynamic study. This contained metoprolol succinate as opposed tometoprolol tartrate which is used in the treatment of angina and hypertension. The preparation used in the clinical trial was an extended-release formulation. After a year the mortality rate was 7.2%in the metoprolol group and 11% in the placebo group. ![]() 1 A placebo-controlled study of 3991 patients who were already on optimum therapy, such as a diuretic and an ACE inhibitor, found that metoprolol significantly reduced deaths. Before new drugs are prescribed, the Committee believes it is important that more detailed information is obtained from the manufacturer's approved product information, a drug information centre or some other appropriate source.Ģ3.75 mg, 47.5 mg, 95 mg and 190 mg controlled-release tabletsĪpproved indication: chronic heart failureĪustralian Medicines Handbook section 6.4.3īeta blockers used to be contraindicated in heart failure, but they can benefit some patients with chronic stable heart failure. However, the Editorial Executive Committee believes that comments made in good faith at an early stage may still be of value. ![]() Some of the views expressed in the following notes on newly approved products should be regarded as preliminary, as there may have been limited published data at the time of publication, and little experience in Australia of their safety or efficacy. ![]()
0 Comments
Leave a Reply. |
Details
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |